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As noted earlier, many of these early model studies that suggested the importance of Fc-dependent effector functions also found that protection was independent of complement, leading to a greater focus on FcR-mediated interactions 87

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Daher B, Parks SK, Durivault J et al (2019) Genetic ablation of the cystine transporter xCT in PDAC cells inhibits mTORC1, growth, survival, and tumor formation via nutrient and oxidative stresses